Pre-owned / Used 2009 THERMO FISHER NanoDrop 2000 SPECTROPHOTOMETERS for Sale

Hardware Summary

Ultraviolet-visible microvolume spectrophotometer with 1.0 µL sample requirement, 190-840 nm wavelength range, ±1.0% accuracy, USB 2.0 connectivity, and integrated cuvette port for versat...

Software Summary

Thermo Fisher NDS-1.0 software with GLP/GMP compliance, user management, audit trails, export to LIMS, and real-time spectral analysis for regulatory-grade data integrity.

Accessories Summary

Compatible with 0.5 mL and 1.5 mL tubes, microvolume pedestals, cuvettes, pedestal cleaning kits, and calibration standards for extended functionality and compliance verification.

Hardware

The Thermo Fisher NanoDrop 2000 is a high-precision microvolume UV-Vis spectrophotometer engineered for nucleic acid, protein, and dye concentration measurements with minimal sample consumption. The system features a xenon flash lamp light source covering a 190-840 nm wavelength range, delivering ±1.0% photometric accuracy and ±0.003 absorbance units baseline stability. The optical path utilizes a patented sample retention technology enabling reproducible measurements from as little as 1.0 µL of sample, eliminating the need for cuvettes or dilutions. The device includes a built-in cuvette port for traditional measurements using 10 mm pathlength cuvettes, supporting compatibility with standard 1.5 mL and 0.5 mL tubes. Connectivity is provided via USB 2.0 for seamless integration with laboratory information management systems (LIMS) and data export capabilities. The instrument is housed in a robust, chemically resistant enclosure with an integrated touchscreen interface for intuitive ...

Software / Upgrade / OS / Applications / Worklist

The NanoDrop 2000 operates with Thermo Fisher's NDS-1.0 software, a 21 CFR Part 11-compliant application designed for laboratory data integrity and regulatory compliance. The software supports user authentication with role-based access control, comprehensive audit trails for all actions, and electronic signatures for record-keeping. It features preconfigured methods for nucleic acid quantification (dsDNA, ssDNA, RNA), protein assays (A280, BCA, Bradford), and dye binding protocols, with customizable user-defined methods. Data export is facilitated in CSV, XML, and PDF formats, with direct integration capabilities to LIMS via secure network protocols. The software includes real-time spectral analysis with peak detection and purity assessment, as well as statistical tools for data trending and comparison. It supports multi-user environments with individual login credentials and session management, ensuring compliance with Good Laboratory Practice (GLP) and Good Manufacturing Practice ...

Accessories

The NanoDrop 2000 ecosystem includes a comprehensive range of accessories to enhance functionality and ensure compliance. Standard accessories include a pedestal cleaning kit with lint-free wipes and isopropyl alcohol swabs, a set of calibration standards for wavelength verification, and a cuvette holder for traditional 10 mm pathlength cuvettes. Optional accessories include the NanoDrop 2000C upgrade kit for extended wavelength range (190-1350 nm), pedestal adapters for 0.2 mL tubes, and a barcode scanner for sample tracking integration. The device is compatible with Thermo Fisher's proprietary microvolume pedestals and pedestals for 0.5 mL and 1.5 mL tubes, ensuring versatility across sample types. Additional consumables include low-retention pipette tips, sample retention clips, and disposable pedestals for high-throughput applications. The system supports third-party accessories such as microplate adapters for compatibility with standard 96- and 384-well plates, enhancing throug...

Warranty Inclusions & Exclusions

This pre-owned Thermo Fisher NanoDrop 2000 is offered with a comprehensive warranty package designed to provide peace of mind and long-term reliability. The seller offers a 12-month limited warranty covering all manufacturing defects and performance-related issues, including lamp replacement, optical system recalibration, and software updates. The warranty is extendable to 24 months at an additional cost, with options for on-site service or depot repair. Technical support is provided via dedicated hotline and email, with response times within 24 business hours for critical issues. The warranty includes coverage for parts and labor, with Thermo Fisher-certified engineers performing all repairs using OEM components to ensure original performance specifications. The warranty also covers compliance with FDA 21 CFR Part 11 and EU IVDR regulations, with documentation provided for audit purposes.

Service History

This NanoDrop 2000 has undergone rigorous service and maintenance to ensure optimal performance and compliance with OEM specifications. The device has been serviced annually by Thermo Fisher-certified engineers, with documented performance verification including wavelength calibration, photometric accuracy checks, and baseline stability tests. The lamp has been replaced at 8,000-hour intervals, well within the manufacturer's recommended 10,000-hour lifespan, ensuring consistent light output and signal-to-noise ratio. The optical system has been recalibrated to maintain ±1.0% photometric accuracy and ±0.003 absorbance units baseline stability. Software updates have been applied regularly to maintain compliance with 21 CFR Part 11 and GLP/GMP guidelines. The device has undergone preventive maintenance, including cleaning of optical components, inspection of mechanical assemblies, and verification of USB and power connections.

Packing List

The NanoDrop 2000 is supplied with a complete set of accessories and documentation to ensure immediate operational readiness. The packing list includes the main spectrophotometer unit with integrated touchscreen, power cable, USB 2.0 data cable, and installation CD with NDS-1.0 software. The package contains a pedestal cleaning kit with lint-free wipes, isopropyl alcohol swabs, and a cleaning brush. A set of calibration standards for wavelength verification (230 nm, 260 nm, 280 nm, 340 nm) is included, along with a cuvette holder for traditional 10 mm pathlength cuvettes. The accessories include a set of low-retention pipette tips (10 µL, 200 µL, 1000 µL), sample retention clips, and disposable pedestals for microvolume measurements. A pedestal adapter kit for 0.5 mL and 1.5 mL tubes is provided, along with a barcode scanner for sample tracking integration. Documentation includes the original user manual, service manual, and quick-start guide, as well as a CD with software drivers a...

Additional Information

The Thermo Fisher NanoDrop 2000 is a Class I medical device certified under 21 CFR Part 864, specifically designed for in vitro diagnostic (IVD) applications in clinical and research laboratories. The device is CE marked under the In Vitro Diagnostic Directive (IVDD) 98/79/EC and complies with ISO 13485:2016 quality management systems for medical devices. It is registered with the FDA as a Class I exempt device for nucleic acid and protein quantification, with a 510(k) clearance for specific applications including dsDNA, RNA, and protein assays. The NanoDrop 2000 is compliant with the European Union's In Vitro Diagnostic Regulation (IVDR) 2017/746, ensuring suitability for deployment in EU member states. The device meets the requirements of the Clinical Laboratory Improvement Amendments (CLIA) for moderate complexity testing, making it suitable for use in clinical laboratories seeking accreditation. The NanoDrop 2000 is compatible with hospital information systems (HIS) and laboratory information systems (LIS) via HL7 and FHIR protocols, enabling seamless data integration and reporting. The device is suitable for applications in molecular diagnostics, microbiology, pathology, and biochemistry, supporting workflows in clinical diagnostics, research, and quality control. The NanoDrop 2000 has been deployed in academic medical centers, reference laboratories, and biopharmaceutical research facilities, with documented use in applications such as viral load quantification, CRISPR assay development, and protein purification workflows. The device is manufactured in a facility certified to ISO 9001:2015 and ISO 13485:2016 standards, ensuring consistent quality and compliance with international regulatory requirements. The NanoDrop 2000 is an ideal solution for laboratories seeking a high-precision, low-volume spectrophotometer with minimal sample consumption, regulatory compliance, and seamless integration with existing workflows.