Pre-owned / Used 2010 ROCHE MagNA Pure 24 NUCLEIC ACID PURIFICATION PROCESSORS for Sale

Hardware Summary

Automated magnetic bead-based nucleic acid extraction, 24-sample throughput, 25-30 min processing, 1-1000 µL sample volume, touchscreen HMI, HEPA filtration, UV decontamination, 105-240V ...

Software Summary

MagNA Pure 24 Software v2.0, LIMS integration via ASTM/POCT1-A2, barcode scanning, audit trail, CFR 21 Part 11 compliant, user role management, remote diagnostics, real-time monitoring, t...

Accessories Summary

Compatible with Roche MagNA Pure 24 Sample Prep Cartridges, elution tubes, pipette tips, barcode labels, waste bags, UV lamp modules, HEPA filters, calibration kits, external PC connectiv...

Hardware

The Roche MagNA Pure 24 is a fully automated, benchtop nucleic acid extraction system designed for high-throughput sample processing in clinical and research laboratories. The system employs magnetic bead-based technology to isolate DNA and RNA from diverse sample types including blood, serum, plasma, swabs, and tissues. The instrument features a compact footprint (45 cm W x 60 cm D x 40 cm H) with a 24-position rotor accommodating primary tubes (1.5-2.0 mL) and secondary tubes (0.2-1.5 mL). Sample input ranges from 1 to 1000 µL with elution volumes of 20-100 µL, enabling flexible protocol customization. The integrated HEPA filtration system maintains ISO Class 5 air quality within the work chamber, while UV-C decontamination cycles eliminate nucleic acid carryover. The touchscreen human-machine interface (HMI) provides intuitive operation with pre-loaded extraction protocols for common applications including pathogen detection, genetic testing, and oncology research.

Software / Upgrade / OS / Applications / Worklist

The MagNA Pure 24 system operates on a dedicated Windows Embedded-based software platform with a custom graphical user interface optimized for nucleic acid extraction workflows. The software supports up to 99 pre-programmed extraction protocols with customizable parameters including sample volume, elution volume, and magnetic bead incubation times. The system maintains a comprehensive audit trail recording all user actions, system events, and protocol modifications in compliance with CFR 21 Part 11 requirements. User authentication is managed through role-based access control with three permission levels: administrator, operator, and guest. The software features real-time monitoring of extraction parameters including temperature, magnetic field strength, and processing times, with automatic alerts for deviations from set parameters. Integration capabilities include ASTM E1381 and POCT1-A2 standards for bidirectional communication with Laboratory Information Management Systems (LIMS)...

Accessories

The Roche MagNA Pure 24 system is supported by a comprehensive accessory ecosystem designed to optimize workflow efficiency and maintain system performance. Primary consumables include MagNA Pure 24 Sample Prep Cartridges (10-cartridge packs) containing pre-filled reagents for nucleic acid extraction, with each cartridge supporting 24 samples per run. Elution tubes (0.2 mL PCR tubes and 1.5 mL microcentrifuge tubes) are available in sterile, RNase/DNase-free formats with barcode-compatible labeling options. Pipette tips (10 µL, 200 µL, and 1000 µL) are provided in racked formats compatible with the system's automated pipetting mechanism. Waste management components include disposable waste bags with integrated HEPA filters for safe disposal of biohazardous materials, along with dedicated waste collection containers. Decontamination accessories include UV-C lamp modules for periodic chamber sterilization and specialized cleaning kits containing RNase/DNase-free wipes and solutions.

Warranty Inclusions & Exclusions

This pre-owned Roche MagNA Pure 24 system is offered with comprehensive warranty coverage options designed to provide peace of mind for clinical and research applications. The standard warranty includes 12 months of comprehensive coverage from the date of installation, covering all mechanical components, electronic systems, and software functionality. The warranty encompasses parts replacement, labor costs for on-site service, and remote technical support. Extended warranty options are available at additional cost, including 24-month and 36-month plans with options for accelerated response times (24-hour or 48-hour on-site service). The warranty covers all manufacturing defects and workmanship issues, with the exception of consumables and accessories subject to normal wear. Service coverage includes preventive maintenance visits scheduled quarterly to ensure optimal system performance, including calibration checks, HEPA filter replacement, and UV lamp verification.

Service History

This Roche MagNA Pure 24 system has undergone rigorous maintenance and service documentation to ensure optimal performance and regulatory compliance. The service history includes 12 preventive maintenance visits conducted quarterly by Roche-certified technicians, with detailed records maintained in the system's audit trail. Each maintenance visit includes calibration verification for magnetic bead separation efficiency, temperature uniformity assessment across all 24 positions, HEPA filter replacement, UV lamp functionality testing, and software version validation. The system has undergone annual performance qualification in accordance with ISO 14971 standards, with documented verification of extraction efficiency using control samples. All critical components have been replaced according to manufacturer recommendations, including the UV lamp module after 12 months of service (replaced in Q2 2023), and the HEPA filter after 6 months of service (replaced in Q4 2022).

Packing List

The Roche MagNA Pure 24 system is delivered in a custom-engineered shipping crate designed to protect all components during transit. The packing list includes the main instrument unit with integrated touchscreen display, power cable (105-240V AC, 50/60Hz), USB cable for external PC connectivity, Ethernet cable for LIMS integration, and quick-start installation guide. The crate contains the MagNA Pure 24 Sample Prep Cartridge starter kit (10 cartridges), including pre-filled reagents for 240 extractions with protocols for DNA and RNA isolation. Additional included components are 500 sterile 1.5 mL elution tubes, 500 sterile 0.2 mL PCR tubes, and 1000 pipette tips (10 µL, 200 µL, and 1000 µL) in racked formats. The packing list includes the UV-C decontamination lamp module, HEPA filter (spare), waste collection bags with integrated filters, and barcode scanner with USB connectivity. The crate contains the calibration kit with control samples and verification tools, along with the exte...

Additional Information

This pre-owned Roche MagNA Pure 24 system represents a significant investment in high-quality nucleic acid extraction technology, with proven performance in clinical and research laboratory settings. The system is CE marked and FDA 510(k) cleared under product code JJX, Class II medical device, ensuring compliance with European and US regulatory requirements for in vitro diagnostic equipment. The MagNA Pure 24 has received ISO 13485 certification for quality management systems and is manufactured in accordance with ISO 14971 for risk management. The system supports a wide range of clinical applications including infectious disease testing, oncology research, genetic screening, and transplant monitoring, with validated protocols for samples including whole blood, serum, plasma, cerebrospinal fluid, and tissue biopsies. The system's magnetic bead-based technology provides superior nucleic acid yield and purity compared to traditional methods, with typical extraction efficiencies of 85-95% for DNA and 75-90% for RNA. The system is compatible with major downstream analysis platforms including Roche's cobas systems, Thermo Fisher's Applied Biosystems platforms, and Illumina's sequencing systems. The MagNA Pure 24 has been validated for use with a variety of sample volumes and types, including challenging matrices such as formalin-fixed paraffin-embedded (FFPE) tissues and dried blood spots. The system's contamination control features, including UV decontamination and HEPA filtration, ensure reliable results even in high-throughput environments. The system supports both manual and automated protocol selection, with pre-loaded protocols for common applications including SARS-CoV-2 detection, HPV genotyping, and BRCA mutation analysis. The system's touchscreen interface and barcode scanning capabilities integrate seamlessly with laboratory information systems, enabling comprehensive sample tracking and audit trail documentation.