Pre-owned / Used 2004 WATERS CORPORATION ACQUITY UPLC LIQUID CHROMATOGRAPHY SYSTEMS for Sale

Hardware Summary

Ultra-high performance UPLC system with 15,000 psi pressure capability, sub-2 µm particle compatibility, and ±1% flow accuracy for precise chromatographic separations in clinical diagnost...

Software Summary

Empower 3 chromatography data software with FDA 21 CFR Part 11 compliance, multi-user access control, audit trails, and seamless integration with laboratory information systems (LIS) for ...

Accessories Summary

Fully compatible with Waters ACQUITY UPLC columns, autosamplers, detectors, and consumables; includes validated HPLC-grade solvent delivery systems and temperature-controlled sample compa...

Hardware

The Waters ACQUITY UPLC system represents a state-of-the-art ultra-performance liquid chromatography platform engineered for high-throughput clinical and materials analysis applications. The system features a quaternary solvent manager with pressure capabilities up to 15,000 psi, enabling the use of sub-2 µm particle columns for enhanced resolution and sensitivity. The binary solvent manager provides precise flow rates from 0.01 to 2.0 mL/min with ±1% accuracy and <0.1% RSD, ensuring reproducible chromatographic separations. The integrated sample manager accommodates up to 96-well plates with temperature control from 4°C to 40°C, reducing sample degradation and improving injection precision. The system includes a photodiode array (PDA) detector with 1.2 nm optical resolution and a dynamic range exceeding 2 AU, ideal for UV-Vis absorbance measurements in pharmaceutical and biochemical assays. The column compartment maintains temperatures from 10°C to 65°C with ±0.

Software / Upgrade / OS / Applications / Worklist

The Empower 3 chromatography data software suite provides a comprehensive, FDA 21 CFR Part 11-compliant platform for data acquisition, processing, and reporting. The software supports multi-instrument control, enabling simultaneous operation of up to four ACQUITY UPLC systems from a single workstation. It features advanced peak integration algorithms with automatic baseline correction, peak splitting, and tailing factor calculations, ensuring accurate quantification in complex matrices. The software includes a robust audit trail system that records all user actions, method changes, and data modifications, with electronic signatures for compliance with regulatory standards. The built-in compliance module supports GxP guidelines, including GLP, GMP, and 21 CFR Part 11, with configurable user roles and access permissions. The system integrates seamlessly with laboratory information systems (LIS) via HL7 or ASTM protocols, enabling automated data transfer and reducing manual data entry ...

Accessories

The ACQUITY UPLC system is compatible with a comprehensive range of accessories and consumables designed to enhance performance and versatility. The system supports Waters ACQUITY UPLC BEH, CSH, and HSS columns, available in 1.7 µm, 2.1 mm, and 3.0 mm internal diameters, optimized for various separation modes including reversed-phase, HILIC, and ion-exchange chromatography. The autosampler accommodates 96-well plates, 384-well plates, and vial racks, with optional temperature-controlled inserts for sensitive samples. The system includes a photodiode array (PDA) detector with a 10 mm flow cell for high-sensitivity UV-Vis detection, as well as optional fluorescence (FLR) and evaporative light scattering (ELSD) detectors for enhanced detection capabilities. The solvent delivery system is compatible with HPLC-grade acetonitrile, methanol, water, and buffer solutions, with optional degassers for improved baseline stability.

Warranty Inclusions & Exclusions

The pre-owned Waters ACQUITY UPLC system is offered with a comprehensive warranty package designed to provide peace of mind and operational reliability. The seller offers a 12-month warranty covering all mechanical and electronic components, including the solvent delivery system, autosampler, detector, and column compartment, with a prorated cost structure for extended coverage options. The warranty includes on-site service by certified Waters technicians, with a guaranteed response time of 48 hours for critical issues and 5 business days for non-critical repairs. The warranty covers parts and labor, with no additional fees for diagnostics or troubleshooting. The seller provides a 30-day money-back guarantee, subject to inspection and verification of the system's operational status upon delivery. The warranty also includes a 6-month supply of consumables, including column frits, seals, and solvent filters, to ensure uninterrupted operation.

Service History

The Waters ACQUITY UPLC system has undergone rigorous preventive maintenance and service procedures to ensure optimal performance and longevity. The system's service history includes annual calibration checks by Waters-certified technicians, with documented compliance to ISO/IEC 17025 standards for testing and calibration laboratories. The solvent delivery system has been serviced with replacement of check valves, piston seals, and degasser membranes, ensuring consistent flow rates and pressure stability. The autosampler has undergone routine maintenance, including cleaning of the needle assembly, replacement of syringe seals, and calibration of injection volume accuracy to ±1% of nominal value. The PDA detector has been serviced with lamp replacement, wavelength calibration, and baseline noise verification to ensure compliance with Waters' specifications. The column compartment has been inspected for temperature uniformity, with recalibration of the heating elements to maintain ±0.

Packing List

The Waters ACQUITY UPLC system is delivered with a complete set of components and accessories to ensure immediate operational readiness. The packing list includes the main ACQUITY UPLC chassis with integrated solvent delivery system, autosampler, PDA detector, and column compartment. The system is accompanied by the Empower 3 chromatography data software suite, pre-installed on a dedicated workstation with Windows 10/11 (64-bit) operating system. The packing list includes all necessary cables and power supplies, including IEC C13 to C14 power cords, USB 3.0 data cables, and Ethernet cables for network connectivity. The system is shipped with a comprehensive set of consumables, including a Waters ACQUITY UPLC BEH C18 column (2.1 x 50 mm, 1.7 µm), column frits, and solvent filters. The packing list includes a 96-well plate adapter, vial racks, and a waste container for solvent disposal. The system is delivered with a detailed user manual, installation guide, and safety data sheets (SD...

Additional Information

The Waters ACQUITY UPLC system is a premium ultra-performance liquid chromatography platform designed for high-throughput clinical diagnostics, materials characterization, and pharmaceutical analysis. The system is manufactured by Waters Corporation, a global leader in liquid chromatography and mass spectrometry technologies, with a proven track record of innovation and reliability in healthcare and research applications. The ACQUITY UPLC system complies with multiple regulatory standards, including FDA 21 CFR Part 11 for electronic records and signatures, ISO 13485:2016 for medical device quality management, and ISO/IEC 17025 for testing and calibration laboratories. The system is CE marked for compliance with EU Medical Device Regulation (MDR) 2017/745, ensuring suitability for use in clinical and diagnostic settings across Europe. The system is also compliant with USP <1225> for validation of compendial methods and ICH Q2(R1) guidelines for analytical method validation, making it ideal for pharmaceutical and biopharmaceutical applications. The ACQUITY UPLC system is compatible with a wide range of clinical assays, including therapeutic drug monitoring, metabolite profiling, and biomarker identification in biological fluids such as plasma, serum, and urine. The system's sub-2 µm particle compatibility enables ultra-fast separations with high resolution, reducing analysis time by up to 80% compared to conventional HPLC systems. This translates to improved workflow efficiency, reduced reagent consumption, and enhanced cost-effectiveness in high-volume clinical laboratories. The system's Empower 3 software supports compliance with Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) guidelines, making it suitable for use in regulated environments such as clinical trials and pharmaceutical manufacturing.