Pre-owned / Used 2023 LGC Biosearch oKtopure Automated Nucleic Acid Extraction System for Sale

Hardware Summary

Automated magnetic bead-based extraction system with 96-well plate throughput, 15-minute processing time, and <1% cross-contamination risk. CE-IVD, FDA-cleared Class II device with ISO 13...

Software Summary

Integrated LGC oKtopure Control Software v2.4 with LIMS compatibility, audit trail logging, and real-time monitoring. Supports HL7/FHIR integration for EHR connectivity and 21 CFR Part 11...

Accessories Summary

Includes magnetic separation module, 96-well deep-well plates, elution tubes, and barcode scanner. Compatible with Qiagen EZ1, Thermo KingFisher, and Roche MagNA Pure systems.

Hardware

The LGC oKtopure automated nucleic acid extraction system is a benchtop Class II medical device designed for high-throughput sample preparation in clinical laboratories. The system employs magnetic bead-based chemistry to isolate DNA/RNA from 1-1000 µL sample volumes with elution volumes ranging from 20-200 µL. Key components include a precision liquid handling robot with <0.5% CV pipetting accuracy, integrated magnetic separation station with 96-well plate capacity, and temperature-controlled elution module maintaining 25±1°C. The device features a 10.1-inch touchscreen interface with LED status indicators and emergency stop functionality. Physical dimensions are 600mm (W) × 550mm (D) × 500mm (H) with 35kg weight. Power requirements include 100-240V AC, 50/60Hz, 200W maximum consumption. The system incorporates HEPA filtration for sample protection and UV-C decontamination cycle for workflow sterilization.

Software / Upgrade / OS / Applications / Worklist

The oKtopure Control Software v2.4 operates on a Windows 10 IoT Enterprise LTSC platform with embedded SQL database for protocol storage. The software provides protocol management with pre-loaded extraction kits including LGC's proprietary oKtopure Blood DNA/RNA kits, Qiagen QIAamp kits, and Roche MagNA Pure kits. Protocol customization allows adjustment of bead binding time (30-300 seconds), wash cycles (1-5), and elution temperature (20-50°C). The system features real-time monitoring with graphical display of magnetic separation efficiency, pipetting precision metrics, and temperature profiles. Audit trail functionality records all user actions, system events, and reagent lot numbers with 21 CFR Part 11 compliant electronic signatures. LIMS integration supports bidirectional data exchange via HL7 FHIR API with Epic, Cerner, and Meditech systems. The software includes automated inventory tracking with barcode scanning capability for reagents and consumables.

Accessories

The accessory ecosystem includes the oKtopure Magnetic Separation Module with 96-well plate capacity and 12-position magnetic rod configuration for optimal bead separation. Consumables include certified 96-well deep-well plates (2.2mL) with skirted design for robotic handling, 0.2mL elution tubes with barcode labels, and pre-filled reagent cartridges for DNA/RNA extraction from blood, saliva, and tissue samples. Additional accessories comprise the oKtopure Barcode Scanner (Honeywell Xenon 1900) for reagent tracking, the oKtopure UV-C Decontamination Module for workflow sterilization, and the oKtopure Temperature Validation Kit for routine system calibration. The system is compatible with third-party kits including Qiagen EZ1 Advanced XL, Thermo KingFisher Flex, and Roche MagNA Pure 96 systems through adapter plates. All accessories carry CE IVD marking and are manufactured under ISO 13485 quality management systems.

Warranty Inclusions & Exclusions

The pre-owned oKtopure system is offered with comprehensive warranty coverage through LGC Clinical's Certified Pre-Owned Program. The warranty includes 12 months of comprehensive coverage from the date of installation, covering all mechanical components, electronic systems, and software functionality. The warranty excludes consumables, accessories, and damage resulting from improper use or unauthorized modifications. Extended warranty options are available for an additional 24 months covering parts and labor, with optional on-site service coverage. The warranty includes preventive maintenance visits every 6 months with system calibration and performance verification. Technical support is provided 24/7 via phone and email with 4-hour response time for critical issues. Remote diagnostics capability allows LGC engineers to troubleshoot system errors without on-site visits. The warranty covers software updates and security patches for the duration of the agreement.

Service History

The oKtopure system has undergone comprehensive service history verification through LGC Clinical's Certified Pre-Owned Program. The system was originally installed in a CAP-accredited clinical laboratory in Q2 2022 and has received regular maintenance according to manufacturer specifications. Service records indicate 24 preventive maintenance visits with documented calibration checks using NIST-traceable standards. The system has undergone three major performance validations including extraction efficiency testing (>98% for DNA, >95% for RNA), cross-contamination assessment (<0.1% between wells), and temperature uniformity verification (±0.5°C). All software updates have been applied according to LGC's release schedule, with version tracking showing compliance with current regulatory requirements. The system has never experienced catastrophic failure and has maintained operational parameters within manufacturer specifications throughout its service life.

Packing List

The complete packing list for the oKtopure system includes the main unit with integrated magnetic separation module, 10.1-inch touchscreen display, and embedded control computer. The accessory package contains the magnetic separation module with 96-well plate holder, oKtopure Barcode Scanner with USB interface, and oKtopure UV-C Decontamination Module. Consumables include two boxes of 96-well deep-well plates (2.2mL capacity), three boxes of 0.2mL elution tubes with barcode labels, and one set of pre-filled reagent cartridges for DNA/RNA extraction. The documentation package includes the oKtopure User Manual (English), Installation and Service Manual, Safety Data Sheets for all reagents, and CE Declaration of Conformity. The calibration kit contains NIST-traceable temperature standards, magnetic separation verification tools, and pipetting accuracy verification kits. The spare parts inventory includes a set of magnetic rods, replacement pipetting tips (10µL, 200µL, 1000µL), and temp...

Additional Information

The LGC oKtopure automated nucleic acid extraction system represents a Class II in vitro diagnostic device manufactured by LGC Clinical, a global leader in molecular diagnostics with ISO 13485 and GMP certification. The system is CE-IVD marked under the European Medical Device Regulation (MDR) 2017/745 and has received 510(k) clearance from the FDA under product code PQA for automated nucleic acid extraction devices. The oKtopure system complies with all relevant international standards including ISO 18113-1 for in vitro diagnostic devices, IEC 61010-1 for electrical safety, and IEC 61326-1 for electromagnetic compatibility. The device is compatible with major laboratory information management systems (LIMS) including Epic Beaker, Cerner Millennium, and Sunquest Copath through HL7 FHIR API integration. Clinical applications include pathogen detection, genetic testing, oncology diagnostics, and forensic analysis. The system supports extraction from a wide range of sample types including whole blood, plasma, serum, saliva, buccal swabs, and tissue samples. Performance specifications include nucleic acid yield of 1-50 µg per extraction with purity ratios (A260/280) of 1.8-2.0 and (A260/230) of 2.0-2.2. The system achieves <1% cross-contamination between wells and maintains sample integrity through HEPA filtration and UV-C decontamination. The oKtopure system is validated for use with FDA-cleared and CE-marked extraction kits including LGC's proprietary kits and third-party systems through adapter compatibility. The device includes built-in quality control features with automatic system suitability testing and electronic audit trails for 21 CFR Part 11 compliance. Environmental specifications include operating temperature range of 15-30°C, humidity range of 20-80% non-condensing, and altitude tolerance up to 2000 meters. The system is designed for continuous operation with mean time between failures (MTBF) of 50,000 hours.