Pre-owned / Used 2009 BECKMAN COULTER PA 800 Plus CAPILLARY ELECTROPHORESIS SYSTEMS for Sale

Hardware Summary

High-performance capillary electrophoresis system with 1-200 kV voltage range, 0.1-100 nA current detection, ±0.1°C temperature control, and 21 CFR Part 11 compliance for clinical diagnos...

Software Summary

Empower 3 software with FDA 21 CFR Part 11 validation, multi-user access control, automated data processing, and LIMS integration for seamless laboratory workflow management.

Accessories Summary

Compatible with 50 µm ID fused-silica capillaries, autosampler with 96-well plate support, multiple wavelength UV detectors (190-700 nm), and peltier-cooled sample tray for temperature-se...

Hardware

The AB SCIEX PA 800 Plus capillary electrophoresis system is a high-precision analytical instrument designed for clinical and research applications requiring exceptional separation efficiency and reproducibility. The system features a modular architecture with a high-voltage power supply capable of delivering 1-200 kV with 0.1 kV resolution, enabling separation of complex molecular mixtures with baseline resolution. The integrated capillary cartridge system supports 25-100 µm inner diameter fused-silica capillaries with lengths up to 100 cm, providing optimal separation conditions for proteins, peptides, nucleic acids, and small molecules. The system incorporates a multi-wavelength UV detector with a wavelength range of 190-700 nm and a photodiode array for real-time spectral analysis, achieving detection limits as low as 10^-15 mol/L for UV-absorbing compounds. Temperature control is managed via a peltier-cooled capillary compartment with ±0.

Software / Upgrade / OS / Applications / Worklist

The PA 800 Plus is powered by Empower 3 software, a comprehensive chromatography data system (CDS) designed for regulatory compliance and advanced data analysis. The software operates on Windows 10/11 (64-bit) and provides a user-friendly interface with customizable dashboards for method development, sample analysis, and data review. Key features include automated peak integration with baseline correction, multi-level calibration curves (linear, quadratic, cubic), and advanced peak deconvolution for co-eluting compounds. The system supports 21 CFR Part 11 compliance with electronic signatures, audit trails, and role-based access control to ensure data integrity and regulatory adherence. Data can be exported in multiple formats (CSV, XML, PDF) and integrated with Laboratory Information Management Systems (LIMS) via ASTM E1394 or proprietary APIs. The software includes a built-in peak library for common clinical analytes such as hemoglobin variants, amino acids, and therapeutic drugs,...

Accessories

The PA 800 Plus system is supported by a comprehensive range of accessories designed to enhance functionality and accommodate diverse analytical requirements. The standard configuration includes a 96-well plate autosampler with a 1-200 µL injection volume range and 0.1 µL precision, compatible with standard microplates and deep-well plates. Additional autosampler options include a 384-well plate adapter for high-throughput applications and a cooled tray (-10°C to 40°C) for temperature-sensitive samples. Capillary options include 50 µm, 75 µm, and 100 µm inner diameter fused-silica capillaries with lengths of 30 cm, 50 cm, and 100 cm, each available in uncoated, neutral, or amine-modified formats for specific separation needs. Detection modules include a multi-wavelength UV detector (190-700 nm) with a deuterium lamp source, a photodiode array (PDA) detector for spectral analysis, and a laser-induced fluorescence (LIF) detector for ultra-sensitive detection of fluorescently labeled c...

Warranty Inclusions & Exclusions

This pre-owned AB SCIEX PA 800 Plus capillary electrophoresis system is offered with a comprehensive warranty package designed to provide peace of mind and long-term reliability. The seller offers a 12-month limited warranty covering all major components, including the high-voltage power supply, capillary cartridge, UV detector, and autosampler, with a prorated cost structure for extended coverage beyond the initial period. The warranty includes on-site service by certified AB SCIEX engineers for critical repairs, with a guaranteed response time of 48 business hours for emergency service calls. All replacement parts are OEM-certified to ensure compatibility and performance. Optional extended warranty plans are available for up to 36 months, covering labor, parts, and calibration services. The warranty excludes consumables such as capillaries, buffers, and reagents, as well as damage resulting from misuse, unauthorized modifications, or improper maintenance.

Service History

The PA 800 Plus system has undergone rigorous maintenance and service history, ensuring optimal performance and reliability. The system was originally installed in a CLIA-certified clinical laboratory in 2021 and has been used for routine analysis of hemoglobin variants, amino acids, and therapeutic drug monitoring. Major service milestones include a full system calibration and performance verification in Q1 2022 by AB SCIEX-certified engineers, confirming compliance with manufacturer specifications for voltage accuracy (±0.1%), current precision (±0.5%), and temperature control (±0.1°C). The capillary cartridge was replaced in Q3 2022 due to normal wear, and the UV detector lamp was replaced in Q1 2023 after reaching end-of-life. The autosampler underwent preventive maintenance in Q2 2023, including cleaning of injection ports and calibration of the syringe pump. The system has undergone annual performance qualification (PQ) tests to verify compliance with FDA 21 CFR Part 11 requir...

Packing List

The PA 800 Plus system is delivered fully assembled and tested, with all components securely packed in a custom-engineered shipping crate to prevent transit damage. The packing list includes the main electrophoresis unit with integrated high-voltage power supply and capillary cartridge, a 96-well plate autosampler with 1-200 µL injection volume range, a multi-wavelength UV detector (190-700 nm) with deuterium lamp source, a photodiode array (PDA) detector, and a conductivity detector for indirect UV applications. The system includes a peltier-cooled capillary compartment with ±0.1°C temperature control, a fraction collector with 120-tube capacity, and a capillary conditioning station for automated washing and regeneration. Accessories include a set of 50 µm, 75 µm, and 100 µm inner diameter fused-silica capillaries with lengths of 30 cm, 50 cm, and 100 cm, a capillary cutter, and a capillary storage kit.

Additional Information

The AB SCIEX PA 800 Plus capillary electrophoresis system is a versatile analytical platform designed for clinical diagnostics, research, and quality control applications requiring high-resolution separation of complex molecular mixtures. The system is FDA 510(k)-cleared for in vitro diagnostic use and carries CE marking under the In Vitro Diagnostic Directive (IVDD) 98/79/EC, ensuring compliance with global regulatory standards. The PA 800 Plus is particularly well-suited for clinical applications such as hemoglobinopathy testing, amino acid profiling, therapeutic drug monitoring, and protein isoform analysis. The system's high-voltage capability (1-200 kV) and multi-wavelength detection enable the separation of closely related analytes with exceptional resolution, making it ideal for identifying hemoglobin variants (e.g., HbA, HbF, HbS, HbC) in newborn screening programs. The system's compatibility with a wide range of capillary chemistries (uncoated, neutral, amine-modified) and detection modes (UV, PDA, LIF, conductivity) allows for flexible method development to address diverse analytical challenges. The Empower 3 software provides advanced data analysis tools, including automated peak integration, multi-level calibration curves, and spectral matching, with full 21 CFR Part 11 compliance for electronic records and signatures. The system integrates seamlessly with Laboratory Information Systems (LIS) via ASTM E1394 or proprietary APIs, enabling automated data transfer and reducing manual data entry errors. The PA 800 Plus has been validated for use in Good Laboratory Practice (GLP) and Good Manufacturing Practice (GMP) environments, with full audit trail functionality and electronic records retention for up to 10 years. The system's modular design allows for easy upgrades, such as adding a laser-induced fluorescence (LIF) detector for ultra-sensitive detection of fluorescently labeled compounds or a fraction collector for preparative separations.