Pre-owned / Used 2022 PALL CORPORATION iCELLis 500+ BIOREACTORS for Sale

Hardware Summary

Large-scale single-use fixed-bed bioreactor with up to 500 m² growth surface, enabling consistent, high-yield production of viral vectors and biologics.

Software Summary

Integrated bioprocess control software with recipe management, real-time parameter monitoring, secure data logging, and GMP compliance features.

Accessories Summary

Compatible with single-use fixed-bed cartridges, tubing assemblies, manifolds, and disposable sensors (not included in this listing).

Hardware

The Pall iCELLis 500+ is a commercial-scale, single-use fixed-bed bioreactor designed to support industrial-level cell culture. With up to 500 m² of growth surface, it delivers high-density adherent cell culture for applications such as viral vector, vaccine, and oncolytic virus production. Its single-use design minimizes contamination risk and eliminates the need for cleaning validation, streamlining workflows for GMP-compliant manufacturing. Compact yet powerful, the system offers reproducibility, scalability, and efficiency, making it well-suited for oncology research, gene therapy development, and large-scale biologics manufacturing.

Software / Upgrade / OS / Applications / Worklist

The system is supported by advanced control software for automated bioprocess management. Operators can monitor key parameters such as temperature, pH, dissolved oxygen, and agitation in real time. Recipe-driven operation allows for consistent process replication, while integrated alarms and audit-ready reporting ensure quality and regulatory compliance. The platform supports data logging, secure storage, and potential integration with MES or LIMS environments. Software updates may enhance security, add functionality, or support new accessories, ensuring long-term usability and compliance.

Accessories

This system works with Pall’s single-use fixed-bed cartridges of varying growth surface sizes, sterile tubing assemblies, manifolds, and fluid handling sets. Disposable sensors, calibration kits, and sampling accessories are also required for full operation. These components are application-specific and not included in this listing. Buyers should confirm required cartridge formats and accessory kits to align with their production processes. Optional add-ons, such as enhanced sensor packages or automation modules, may be available depending on supplier configuration.

Warranty Inclusions & Exclusions

This system may be offered with a limited functional warranty covering hardware integrity and basic operational performance. Warranty typically excludes consumables, single-use cartridges, tubing sets, and operator-related damage. Extended warranty, preventive maintenance packages, and compliance validation services may be available separately. Buyers should confirm warranty scope, duration, and available service options with the supplier prior to purchase.

Service History

Service history for this specific unit is not included in this listing. Depending on supplier records, the system may have undergone preventive maintenance, calibration, or refurbishment prior to resale. Buyers are advised to request documentation such as calibration certificates, validation reports, or service records to ensure system readiness and compliance with intended use.

Packing List

Pall iCELLis 500+ Bioreactor Main Unit Power connections User manuals and documentation (if available) Note: Cartridges, tubing, sensors, and consumables are not included unless explicitly stated.

Additional Information

The iCELLis 500+ is widely used for commercial-scale production of viral vectors, vaccines, and advanced biologics. Its single-use platform reduces downtime between batches and enhances process safety. Applications include oncology research, gene therapy, and vaccine development. Installation, operator training, and validation services are often offered separately. Buyers should review facility compatibility, utility requirements, and accessory needs before purchase.